Mouse models are often used as preclinical models of human disease, but the number of drugs that succeed in mice but go on to be approved as a drug for humans is only about one in ten. A new study comparing gene expression in the cells of human brains with those of mouse brains sheds new insight into why.
from Science-Based Medicine https://sciencebasedmedicine.org/one-reason-mouse-studies-often-dont-translate-to-humans-very-well/
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